Senior Manager, Threat Remediation

Our Global Cyber Defense team is responsible for safeguarding Pfizer’s digital assets and infrastructure through proactive threat detection, response, and risk mitigation across on-premises, cloud, and hybrid environments.

The Senior Manager, Threat Remediation is responsible for owning and driving the end‑to‑end remediation of cybersecurity threats across the enterprise. This role sits at the intersection of threat detection, incident response, vulnerability management, offensive security and technology risk, ensuring that identified threats are prioritized, mitigated, and resolved in a timely, risk‑based, and compliant manner.

This role will work closely with the SOC, Cloud Services, Infrastructure, End User Computing, Engineering, GRC, Legal, Privacy, and Business stakeholders to reduce cyber risk and improve the organization’s overall security posture.

• Own the threat remediation lifecycle, from intake of identified threats (incidents, alerts, vulnerabilities, control gaps) through containment, mitigation, and closure.

• Translate threat intelligence, SOC findings, red team results, penetration tests, and vulnerability scans into actionable remediation plans.

• Ensure remediation actions are risk‑based, prioritized, and aligned with business impact, regulatory exposure, and threat severity.

• Partner with Incident Response and SOC teams during active incidents to ensure effective containment and eradication strategies.

• Lead post‑incident remediation efforts, ensuring root cause analysis (RCA) is completed and systemic issues are addressed.

• Track and validate completion of corrective and preventive actions (CAPAs) resulting from incidents.

• Work with IT, engineering, and application owners to resolve vulnerabilities while respecting validated system change controls.

• Ensure compensating controls are documented and approved where remediation is constrained due to regulatory or operational limitations.

• Define and report on remediation KPIs and KRIs (e.g., mean time to remediate, overdue critical findings, repeat issues).

• Provide executive‑level reporting on remediation status, risk reduction, and systemic weaknesses.

• Support internal and external audits, regulatory inspections, and security assessments by demonstrating effective remediation governance.

• Partner with detection, threat intelligence, and vulnerability teams to close gaps between detection and remediation.

• Contribute to long‑term cyber defense strategy, including roadmap planning and technology selection.

• Bachelor’s degree in Computer Science, Information Security, Engineering, or a related technical discipline, or equivalent experience.

• 7+ years of experience in cybersecurity, with hands-on involvement in remediation, vulnerability management, security engineering, or incident response.

• Strong understanding of:

  • Threat actor tactics, techniques, and procedures (MITRE ATT&CK)

  • Incident response and containment strategies

  • Vulnerability management and remediation workflows

  • Cloud security (AWS, Azure, GCP)

  • Endpoint, network, identity, and application security

• Familiarity with SOC tooling (SIEM, SOAR, EDR/XDR), vulnerability scanners, and ticketing/workflow systems.

• Demonstrated experience in an agile work environment possessing qualities such as a collaborative mindset, adaptability to change, and a proactive problem-solving approach.

• Leadership experience managing or mentoring analysts and engineers.

• Working knowledge of GxP, FDA 21 CFR Part 11, EMA, HIPAA, GDPR, and other relevant regulations.

• Familiarity with security frameworks, risk management practices, and regulatory expectations relevant to pharmaceutical or life sciences organizations.

• Professional certifications such as CISSP, CISM, GIAC, or equivalent credentials related to security operations or risk management.

Please apply by sending your CV and a motivational letter in English.

Work Location Assignment: Hybrid

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